illustration of DNA strand and abstract shapes on a computer screen on a green gradient background

Medical, health, and genomics

Digital pathology helps decode tumor microenvironments for precision immunotherapy. GigaPath is a novel vision transformer that can scale to gigapixel whole-slide images by adapting dilated attention for digital pathology. In joint work with Providence and UW, we’re sharing Prov-GigaPath, the first whole-slide pathology foundation model pretrained on large-scale real-world data, for advancing clinical research and discovery.

GigaPath: Whole-Slide Foundation Model for Digital Pathology

Research Forum Ep2 | Panel | Transforming the Natural Sciences with AI

Research Forum 2 | Panel Discussion: Transforming the Natural Sciences with AI

white icons of first aid kit, DNA strand, laptop monitor with overlapping eye, and microscope on a blue and green gradient background

Scaling early detection of esophageal cancer with AI

female doctor / nurse reviewing a tablet

Microsoft Health Futures

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Published Date

Publication

Causal integration of chemical structures improves representations of microscopy images for morphological profiling

Yemin Yu, Neil Tenenholtz, Lester Mackey, Ying Wei, David Alvarez-Melis, Ava P. Amini, Alex Lu

April 2025

Github

Microsoft Research Blog

Research Focus: Week of April 7, 2025

April 9, 2025

In this issue: We introduce a new dataset designed to assist renewable energy infrastructure planners, a new method for denoising MRI imagery, and an AI tool for analyzing distant galaxies. Check out our latest research…

Podcast

Real-world healthcare AI development and deployment—at scale

April 3, 2025

Microsoft’s Dr. Matthew Lungren and Epic’s Seth Hain discuss the challenges and opportunities of leveraging generative AI for enhanced patient care and improved clinical documentation and recordkeeping at scale—plus what’s next for the technology in…

AI Revolution podcast | Episode 2 - AI Revolution podcast | Episode 2 - Real-world healthcare AI development and deployment—at scale | outline illustration of Seth Hain, Peter Lee, Dr. Matthew Lungren | outline illustration of Seth Hain, Peter Lee, Matt Lungren

Publication

Toward deep learning sequence–structure co-generation for protein design

Chentong Wang, Sarah Alamdari, Carles Domingo-Enrich, Ava P. Amini, Kevin Kaichuang Yang

Current Opinion in Structural Biology | March 2025

Microsoft Research Blog

Research Focus: Week of March 24, 2025

March 26, 2025 | Qianhui Wu, Huiqiang Jiang, Xufang Luo, Hao Cheng, Dongsheng Li, Yuqing Yang, Chin-Yew Lin, Lili Qiu, Jianfeng Gao, Yangyu Huang, Tengchao Lv, Lei Cui, Scarlett Li, Furu Wei, Xenofon Foukas, Bozidar Radunovic, Margus Veanes, Sarah Alamdari, Carles Domingo-Enrich, Ava Amini, Kevin Kaichuang Yang, Peter Lee, Ade Famoti, Christopher Bishop

In this issue, we examine a new conversation segmentation method that delivers more coherent and personalized agent conversation, and we review efforts to improve MLLMs’ understanding of geologic maps. Check out the latest research and…

Publication

SNRAware: Improved Deep Learning MRI Denoising with SNR Unit Training and G-factor Map Augmentation

Hui Xue, Sarah M. Hooper, Iain Pierce, Rhodri H. Davies, John Stairs, Joseph Naegele, A. Campbell-Washburn, Charlotte Manisty, James C. Moon, T. Treibel, Peter Kellman, Michael Hansen

March 2025

Under review

Project

Dataset Source Code

Immunomics – JL-GloVe

We employ GloVe and random projection theory to infer immunologically meaningful T-cell receptor embeddings from adaptive immune repertoires. This repository contains the Pytorch code to replicate experiments in our paper “Scalable Universal T-Cell Receptor Embeddings…

GitHub Publication

Podcast

The reality of generative AI in the clinic

March 20, 2025

UC San Diego Health’s Dr. Christopher Longhurst and UC San Francisco Health’s Dr. Sara Murray explore how generative AI is changing patient care, clinical workflows, and decision-making and how they envision the technology impacting the…

Podcast

The AI Revolution in Medicine, Revisited: An Introduction

March 6, 2025

Host Peter Lee, Microsoft Research president, discusses the motivation behind the new series and the GPT-4 encounter that helped him view the tech not only as a potential tool for improving healthcare but a chance…

AI Revolution podcast | Episode 0 - A brief introduction from Peter Lee | outline illustration of Peter Lee

Microsoft Research Blog

Advancing biomedical discovery: Overcoming data challenges in precision medicine

March 5, 2025 | Mandi Hall

Our recent study in Nature Scientific Reports identified key challenges in the biomedical data lifecycle and offered 7 actionable recommendations.

Medical, health, and genomics

Highlights